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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8149ff1b2112e8ee9d68ebc8fac1090e8a15d80aeba54fbeb2a3f69b1b4dc01' 
  AND token = 'tCmFYbaRLMCOgmsQcPgi1A5g3JoW8pj7zaDRZ8tM07k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}