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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0268633e2bd44917db96485fc747a3c4b0d164b4720e7467d328e1fbb43bf6cf' 
  AND token = 'YRIFcwasSKh44r/7YpnsYO4zZvdisNNjGlUh5xuaz00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}