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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c53f577e6ea7a9fc41e8048e97ecc1a04d4ab1998a5073bfa86333f3c711778b' 
  AND token = 'k0YnQ+fSU0wfB2FqkNH4PwH3Sdf2FPhzTS5+1p3zY28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}