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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37c263cd0a7edb59dd5c1c9b82a2d545a60375031772a03b95cf31e0b78d2ece' 
  AND token = '78TWSVVYBhgNSUj1gya5EL6O9miVGTGtgRPExdM+tVo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}