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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '453a0629b74fba9b287fd3b93a14161f9b09ae560eaa4a2018c80dc8e27ec312' 
  AND token = '+MDjgLEBDdWKs2rhHOKN5D9kjLIGxWD2BCSivzfn3Lo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}