SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5372af04c5c35b8ac02f713cbf9ca7ed09b6bb8e6d8d774db814acb266617132' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}