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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ec0d45a82f8c2e40eadf955f4c07fbeab855cec3695b76ff82d654053f77310' 
  AND token = 'cW+5YASCMmZN7EQ0uvULZeMem1bq1D4qbUzQ2vehD8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}