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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5391cfe9ddc89f40846b01c69a0b1dcc3f0b03241b93b399b341f758cd0fa00f' 
  AND token = '1Q2x6O2v4XQ2z3cqWQrrzoK5zbxAvlBQiqhlVYf67C0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}