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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81bb1ecacef5f8d22789b50cdc99e911e19d568ed5b5a4a9f7f13711ce0f140d' 
  AND token = 'EYJ46RKoCQlT5FYs0vQS5HPO3E9I1FvLLlruMTn0XCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}