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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4813cc961c4151974c459391e962eb1266005f6d76decb00f0669d4f4da589e4' 
  AND token = 'E0PCE8LEC8OLGXvUEzYRT/I7CvSSTSYO1f7ZDHDrA68=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}