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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd6ffcf730d6b3aac1daf51e698a541cdc58d18347a4e53f895301c2e5a3cf65' 
  AND token = 'saK/O6a5fDIePugwaobeXh4Hqb4godoIEut/75igB9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}