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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4d00779cf4e3ad0a529da8f86c1449c32832839feff34dc9448ad1aca2fbca9' 
  AND token = 'pc/OJIrLGCDnuMVuQGLuTgm4+uQjmr/PTUcDJk7ZMRk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}