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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8001175dc1c8c39f6220f29209c17deb49cbf1de01c4cbb770c24cbe98bc0345' 
  AND token = 'f95ZMrGh/KkZYK4mSsll3Lr/5rAK3C0pX9gmhdqmkcc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}