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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '241da6d59ba6ad514bc1682c4d92a86bc6d7cb2f8da0dcb4884d076853bf253b' 
  AND token = 'UC4zdQ4n4SBVxRYWumLy26Ddgs7dzPGRrmCC7e0bfP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}