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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3b496c0a14714b9ac7babb9b0057c040a54f38fa5cdf090e98a99921ff03e21' 
  AND token = 'x+FY813zHJYE7m0HO1uNBtnbNfdrDMt0hnOnvJGP0d8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}