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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78e5a1f6d1f135d74c011ae3c63e4f967370f861429a0983792d6f6553f30112' 
  AND token = 'yTPptGqRNe9pXd4SbH6ubwzR5lbisUUQ4eANSgHWoe0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}