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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a59458c2acda515d62943a1fa256d38169118f1d70b8346b983575f4a1350654' 
  AND token = 'W2P8WR3Y3yqRNuhkirXE3q4qsq4atT6Y/CW3SqpMAhE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}